Re complex systems for electrode modification; (ii) a few of the CeO2- and AuSNPs/CeO2-modified SNGC electrodes are rather sensitive with a comparatively higher linear range simultaneously; besides, these modified electrodes are quick of fabrication, low expense and may be utilized for a lot of instances, showing higher reproducibility and repeatability; (iii) the electro-oxidation signal corresponding to AA seems at significantly less good potentials values (0.140 V) than the majority of methodologies reported in literature. This analysis suggests that these modified electrodes might be very promising voltammetric sensors for the determination of AA. It must be taken into consideration that there are only a number of papers (see Table 4) reporting determination of AA with CeO2-modified electrodes and that up to the extent of our know-how this is the very first time that AA has been determined by means of a AuNPs/CeO2 nanocomposite-modified electrode. Moreover, when comparing our program with other electrochemical quantification techniques for AA, it can be noteworthy that DPV may be the most extended technique to identify AA. In line with Table four, amperometry results in lower detection limits than standard voltammetric techniques as CV or DPV, and when applying SWV results are rather very good, becoming inside a related variety than those obtained for DPV. Nevertheless, when taking a look at DPV only, it seems that the improvement in the figure of merits depends strongly around the electrochemical device employed, and mostly in the modification from the electrode. Our devices, modified with CeO2 nanoparticles and AuSNPs/CeO2 nanocomposite, as stated prior to, performs rather well, with decrease detection limits and greater dynamic variety than other far more complicated modified devices such as -CD-nanoAu/Fc-ITO, AuNPs/silica/MWCNT/GCE or AuNPs/-CD/graphene/GCE. Apart from, some other advantages, as those described above, might be noted as well. three.3. Actual Sample Application Some tests from the electrochemical devices used all through this work were done to figure out ascorbic acid (vitamin C) in industrial apple juices for babies. The determination of AA in the true samples was carried out by the regular addition method so that you can stop any matrix effects. In addition, the results obtained by the electroanalytical methods had been compared with these obtained by HPLC, taken as a reference system. It truly is noteworthy that this really is the initial time that electrochemical sensors based on the nanocomposite as the one reported in this function has been applied towards the determination of AA in commercial apple juices for babies as true sample.355819-02-2 custom synthesis Sensors 2013, 13 Table four.6-Bromo-2-fluoro-3-nitropyridine manufacturer Comparison of distinctive CeO2-, AuNPs- and AuNPs/CeO2- modified electrodes for AA determination.PMID:23439434 Electrode D-nanoAu/Fc-ITO Functionalized-AuNPs/GCE Au-PtNPs/Cys self-assembled/ITO AuNPs/PANI/GCE AuNPs/silica/MWCNT/GCE AuNPs/ D/graphene/GCE AuNPs/TiO2/Ti AuSNPs/SNGC MWCNT/GCE PEDOT/Ni/Si/MCPE SGN/NiPc polyXa/MWCNT/GCE CTAB/ABPE GCE2 CeO2/GCE PdNPs/CeO2/GCE CeO2/SNGC3 AuSNPs/CeO2/SNGC4 Approach CV Amperometry CV Amperometry DPV SWV DPV DPV SWV DPV DPV Amperometry 2nd od LSV DPV DPV DPV DPV DPV LOD 1 ( ) four.1 0.14 1 0.5 220 ten 400 three.71 1.4 ten 0.45 0.1 1 23.38 1.50 —1.59 2.93 Linear Range ( ) 53?,000 eight?,000 2?00 three?0,000 1,000?,000 30?,000 1,000?,000 1.5?,000 four.7?,000 20?,400 90?,110 1?,520 two?,000 25?00 5.0?,000 100?00 1.5?,000 1.5?,000 E (V) 0.572 0.320 0.250 0.300 0.220 0.222 0.350 0.104 0.315 0.030 0.300 0.300 0.284 0.010 0.092 -0.083 0.156 0.140 Refs. [46] [47] [48] [49] [50] [51] [41] [9] [52] [53] [54] [55] [56].